Biopharmaceuticals

Instrumentation requirements in biopharmaceutical production go beyond "accurate measurement" tofull process verifiability and traceable records. Fermentation, purification, compounding and lyophilisation processes commonly involve repeated high-temperature sterilisation (CIP/SIP) and long-cycle continuous cultivation; the stability of process temperature control directly affects batch pass rates and GMP inspection results.

Common challenges:Sensors repeatedly withstand high-temperature sterilisation, imposing high demands on service life and drift control; cleanroom installation space is limited, with explicit requirements for hygienic connections and surface finish; control systems, validation systems and recorders often require the same signal, and direct parallel connection introduces interference; processes using organic solvents also carry explosive atmosphere risks.

Our solution:Temperature sensors and transmitters cover key temperature points in fermenters, seed tanks, purified water and water-for-injection systems, lyophilisers and sterilisers, supporting small-diameter hygienic connections and local display; signal isolators provide mutually independent, galvanically isolated signal distribution to control systems and validation/recording systems, ensuring consistent readings at both; Zener barriers provide intrinsic safety protection in solvent areas; digital input isolation converter modules safely transmit equipment status and alarm signals.

The solution helps enterprises simultaneously achievetemperature control stability, batch record consistency and audit readinessacross all three aspects, reducing repeated commissioning during the validation phase.

• Temperature control for fermenters, seed tanks and feed tanks
• Temperature, level and flow in purified water / water-for-injection systems
• Temperature recording loops for lyophilisers, sterilisers and compounding tanks
• Isolated transmission of cleanroom equipment operating status and alarm signals